The Longevity Reality Radar
46 approaches, rated by evidence.

Mitochondrial transplantation

Mitochondrial transplantation & mtDNA repair. Aging itself. Reviewed Jul 2026.

Mitochondrial DNA damage rising after 60 is documented, but correcting it has only been shown in mice and no human transplant data exist.

Stage
Preclinical
Rung: Experimental. Animal, lab or theoretical. Years away, if ever.
Evidence grade
D
mouse and lab
Animal or lab only, single pilot, or case reports. How grades work.

What it is

Replacing or repairing the cell's own mitochondrial genome — which a 2026 Nature paper shows mutates sharply after age 60 — plus tackling clonal hematopoiesis in blood stem cells.

The evidence

Nature (2026): mtDNA mutation burden rises sharply after 60. Sinclair-lab work shows resetting nuclear gene expression corrects key mitochondrial aging defects in mice. Human mito-transplant remains future/preclinical.

What you can do today

Not available for this use, and years away if it arrives at all. Anything sold today with this claim is not backed by human evidence for it.

Sources

  • Coverage, not a sourcex.com

No primary paper or registry record is linked for this entry yet. The evidence summary names the studies it relies on.

Change history

No ladder moves or corrections logged for this entry yet. Changes are dated on the change log.

Related

More in Aging itself

All 17 in Aging itself.

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